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Efficient and simple pathway for a non-protein amino acid synthesis


A simple and efficient approach to the synthesis of β-N-methylamino-L-alanine (BMAA)” in Tetrahedron Letters (2014), DOI: 10.1016/j.tetlet.2014.02.037

by Enzo B. Arévalo-García and Juan Carlos Colmenares Q.

Our manuscript creates a model for future studies on the synthesis of analogues of BMAA. It also highlights some important features:

1. Efficient and simple pathway for a non-protein amino acid synthesis.
2. Complete maintenance of stereochemical integrity of the target molecule.
3. β-N-methylamino-L-alanine prepared in very good yields under mild reaction conditions, simple work-up and short reaction times


Efficient and simple pathway for a non-protein amino acid synthesis
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